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Influence of paternal age on the risk of spontaneo...[Am J Epidemiol. 2005] - PubMed Result
The frequency of chromosomal anomalies in spermatozoa appears to increase with male age. Because these anomalies play a role in the etiology of Spontaneous abortion, an influence of paternal age on risk of Spontaneous abortion is plausible but not established. The aim was to characterize this influence in a prospective study among 5,121 California women, who as members of a prepaid health plan were interviewed in 1990 or 1991 when they were less than 13 weeks' pregnant and who were followed until the end of pregnancy. The risk of Spontaneous abortion between weeks 6 and 20 of pregnancy was studied using a Cox model adjusted for maternal age. The adjusted hazard ratio of Spontaneous abortion associated with paternal age of 35 years or more, compared with less than 35 years, was 1.27 (95% confidence interval: 1.00, 1.61), with no modification by maternal age. Among women aged less than 30 years, the hazard ratio of Spontaneous abortion associated with paternal age of 35 years or more was 1.56 for first trimester Spontaneous abortion and 0.87 for early second trimester Spontaneous abortion (test of interaction, p = 0.25). In conclusion, the risk of Spontaneous abortion increased with increasing paternal age, with a suggestion that the association is stronger for first trimester losses.
Abortion, Spontaneous
Abortion, Spontaneous [C13.703.039]
Search of: Open Studies | "Abortion, Spontaneous" - List Results - ClinicalTrials.gov
Open Studies | "Abortion, Spontaneous"
MedlinePlus: Abortion
MedlinePlus: Abortion
spontaneous abortion
chronic Spontaneous abortion
chronic spontaneous abortion
chronic Spontaneous abortion
Search of: "Abortion, Spontaneous" - List Results - ClinicalTrials.gov
"Abortion, Spontaneous"
Should Spontaneous Abortion be Prevented?
Should Spontaneous Abortion be Prevented?
MedlinePlus
Medical Encyclopedia: Miscarriage
If a miscarriage occurs, the tissue passed from the vagina should be examined to determine if it was a fetus or a hydatidiform mole . It is also important to determine whether any fetal tissue remains in the uterus. This is called an incomplete Spontaneous abortion.
Spontaneous Abortions Possibly Related to Ingestion of Nitrate-Contaminated Well Water -- LaGrange County, Indiana, 1991-1994
Health effects associated with ingestion of nitrate-contaminated water have included methemoglobinemia (i.e., blue baby syndrome) in infants (1) and Spontaneous abortions in laboratory animals and livestock (2,3); however, only one study in humans has reported an association between increased methemoglobin levels and Spontaneous abortion (4). During March 1993, the LaGrange County (Indiana) Health Department (LCHD) identified three women who reported a total of six Spontaneous abortions during 1991-1993 and who resided in proximity to each other; each had obtained drinking water from nitrate-contaminated private wells in LaGrange County (1995 population: 29,350). LCHD was subsequently notified about a fourth woman from another part of the county who had had two Spontaneous abortions after she had moved into a new home with a nitrate-contaminated private well. This report summarizes the investigations of these reports by LCHD, which indicate the need for further assessment of a possible relation between ingesting nitrate-contaminated water and Spontaneous abortion.
1985.06.28 DAB665 California Department of Health Services
Spontaneous abortion involves a wanted pregnancy that the mother loses
Abortion, Miscarriage, and Breast Cancer Risk - National Cancer Institute
The relationship between induced and Spontaneous abortion and breast cancer risk has been the subject of extensive research beginning in the late 1950s. Until the mid-1990s, the evidence was inconsistent. Findings from some studies suggested there was no increase in risk of breast cancer among women who had had an abortion, while findings from other studies suggested there was an increased risk. Most of these studies, however, were flawed in a number of ways that can lead to unreliable results. Only a small number of women were included in many of these studies, and for most, the data were collected only after breast cancer had been diagnosed, and women’s histories of miscarriage and abortion were based on their “self-report” rather than on their medical records. Since then, better-designed studies have been conducted. These newer studies examined large numbers of women, collected data before breast cancer was found, and gathered medical history information from medical records rather than simply from self-reports, thereby generating more reliable findings. The newer studies consistently showed no association between induced and Spontaneous abortions and breast cancer risk.
Abortion, Threatened
Abortion, Spontaneous [C13.703.039]
Abortion Surveillance --- United States, 2000
maternal deaths for 1999 that were thought to be potentially related to abortion. These maternal deaths were identified either by some indication of abortion on the death certificate or from information such as a news report associated with the death. Investigation of these cases showed that 10 of the 22 deaths in 1998 and four of the 17 deaths in 1999 were related to legal induced abortion and none to illegal induced abortion ( Table 19 ). For 1998, 11 deaths were due to Spontaneous abortion, and one death was found not to be abortion related. For 1999, 10 deaths were due to Spontaneous abortion, and three deaths were found not to be abortion related. Numbers of deaths due to legal induced abortion were highest before the 1980s, with very few deaths occurring in 1999 ( Table 19 ). Possible abortion-related deaths that occurred during 2000--2002 are currently being investigated.
Energy Citations Database (ECD) - - Document #5600340
NIOSH conducted a study of 2,430 female telephone operators to determine if exposure to electromagnetic fields emitted by video display terminals (VDT`s) were associated with increased risk of Spontaneous abortion.^Exposure levels were determined using company records of weekly hours of VDT use and measurements of electromagnetic fields at VDT workstations.^Operators who used VDT`s had higher abdominal exposure to very low frequency (VLF) (15 kHz) electromagnetic.^Workstations without VDT`s did not emit VLF energy.^Abdominal exposure to extremely low frequency (ELF) (45 to 60Hz) was similar for operators who used VDT`s and those who did not.^The authors found no excess risk of Spontaneous abortion for VDT use in the first trimester of pregnancy and no dose-response relationship resulting from weekly hours of VDT use.^Significant associations were found for other risk factors e.g. cigarette smoking, thyroid disorder, alcohol consumption.^The potential association of Spontaneous abortion and physical or psychological stress could not be addressed in the study design.^The authors conclude that VDT use and exposure to the accompanying electromagnetic fields were not associated with an increased risk of Spontaneous abortion in the study.
Impact of perceived HIV risk, history of child loss and spontaneous abortion on desire for pregnancy among ever-married women in Zimbabwe.
BACKGROUND: In a background of very high prevalence of HIV infection among women of child-bearing age and increasing demand for treatment to prevent mother to child transmission, we investigated the impact of perceived HIV risk, reporting at least one child death and Spontaneous abortion in the past five years on the desire for future pregnancy in a population-based sample of women in Zimbabwe. METHODS: A random, cross-sectional sample of 2,250 ever-married women age 15-49 years was selected from 6,828 households in rural and urban Zimbabwe. One eligible subject was selected per household for a structured interview on factors associated with desire for future pregnancy. RESULTS: Overall, 54% of subjects desired to get pregnant in future, 55% perceived themselves at high risk for HIV infection, 6% reported the death of at least one child and 12% reported at least one Spontaneous abortion in past five years. In multiple logistic regression analysis, reporting at least one child's death (OR=1.77; 95% CI 1.13-2.78) and at least one Spontaneous abortion in past five years (OR=1.81; 95% CI 1.08-3.04) were significantly associated with a higher desire to get pregnant; however, perceived high risk for HIV infection did not (OR=0.85; 95% CI 0.67-1.09). CONCLUSIONS: Perceived high risk for HIV infection was not associated with lower desire for future pregnancy. In fact, our data suggest an increased desire for future pregnancy to replace childhood deaths or Spontaneous abortions that may result from HIV infection. Voluntary HIV testing services are challenged with balancing counseling messages on the strong desire for children, the risk of mother to child transmission, poor fetal outcome, and the limited availability of treatment to prevent vertical transmission. Further research is needed to explore utilitarian-economic, social and psychological values attributed to children by women and their partners.
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Abortion, Spontaneous -
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10061616 (ABORTION Spontaneous COMPLETE)
Studies by Topic - ClinicalTrials.gov
Abortion, Spontaneous 65 studies
HIV infection as a risk factor for spontaneous first trimester abortion.
OBJECTIVE: To determine whether HIV infection and other sexually transmitted diseases (STD) are risk factors for Spontaneous first trimester abortion. METHODS: A case-control study was carried out at the Dept. of OBS/ GYNE, Kenyatta National Hospital, Nairobi, Kenya. 135 pregnant mothers presenting with signs and symptoms of a first trimester abortion were enrolled as cases. Excluded from the analysis were women whose abortion was probably induced (based on the history and/ or physical examination). 135 controls were selected at random from mothers at the antenatal clinic, with a gestation beyond 20 weeks. Data collection included sociodemographic features, sexual and medical history, clinical signs and symptoms, serology for HIV and syphilis, and microbiology for N. gonorrhoeae, C. trachomatis, S. agalactiae, M. hominis, U. urealyticum, T. vaginalis and bacterial vaginosis. RESULTS: 20 out of 135 women were excluded based on the suspicion of the abortion being induced. Although the HIV seroprevalence was higher in the abortion group as compared to the controls (10.4% versus 5.2%, p = 0.12; p = 0.12) the difference did not reach statistical significance. Spontaneous first trimester abortion was associated with positive syphilis serology (13.7% of the cases versus 1.3% of the controls, p = .009, OR = 12.2, 95% CI 1.5-79.5) and with maternal colonisation with S. agalactiae (16.8% vs 3.8%, p = .001, OR = 5.1, 95% CI 1.7-16.4). No association was found between other STD and Spontaneous first trimester abortion. CONCLUSION: These preliminary results suggest that maternal HIV infection is not significantly associated with Spontaneous first trimester abortion in the population studied.
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